Blogs
GP Monitoring of Those on Antidepressants
By DUNCAN DOUBLE Tony Kendrick, who I have mentioned before (see eg. previous post) is the first author of a paper about antidepressant withdrawal in general practice. It found that more than 40% of patients could discontinue their antidepressant treatment in a clinical trial, comparing whether adding internet and telephone support to family practitioner review
Mainstream Psychiatry Continues to Minimise Significance of Antidepressant Withdrawal
By DUNCAN DOUBLE Mainstream psychiatry has minimised the significance of antidepressant withdrawal, as I first pointed out in a BMJ letter in 1997. My complaint then was that the Defeat Depression Campaign, launched in January 1992 by the Royal College of Psychiatrists in association with the Royal College of General Practitioners, advocated educating patients and
On the Neuroplasticity Hypothesis of Antidepressant Action
By MARK HOROWITZ On the neuroplasticity hypothesis of antidepressant action – I worked in a neurogenesis laboratory for 4 years and completed my PhD partly on this topic (For SSRIs). We treated human hippocampal stem cells with different combinations of chemicals and looked for neurogenesis with cell markers. One of the things that happened often
Busting Myths about Psychosis & Antipsychotics with Prof Joanna Moncrieff
In this talk, Prof Joanna Moncrieff (University College London) looks at the evidence behind some common myths relating to psychosis and ‘antipsychotic’ drugs: the idea that psychosis or ‘schizophrenia’ are neurodegenerative conditions; the concept of the ‘untreated duration of psychosis’ and whether early drug treatment produces better outcomes; the famous dopamine hypothesis of schizophrenia; the
Adapting to Individual Differences
// By Duncan Double // Rach Idahu has a blog ‘Adulting with ADHD’. BBC News reports that she told BBC Podcast ‘Access All’ that she lost £200 when she late checked in for a flight, even though she did not realise she was late (see article). The article explains that Rach estimates she has lost
Upcoming online conference by IIPDW
We are pleased to announce this second instalment of the International Institute for Psychiatric Drug Withdrawal conference series. If you are interested to join, please register at Eventbrite (click on the image above or follow this link: https://withdrawal-from-psychiatric-drugs-2.eventbrite.co.uk ). A detailed programme can be viewed (and downloaded) below:
Chemical Imbalance Theory of Depression: Clearing Up Some Misconceptions
By MARK HOROWITZ (UCL) and JOANNA MONCRIEFF (UCL) The scale of the response to our recent study finding that there was no support for the idea that low serotonin causes depression – the so-called “chemical imbalance” theory of depression – was enormous. Our paper is one of the 400 most shared of the 21 million
Depression is Probably Not caused by a Chemical Imbalance in the Brain – New Study
By JOANNA MONCRIEFF (UCL) and MARK HOROWITZ (UCL) For three decades, people have been deluged with information suggesting that depression is caused by a “chemical imbalance” in the brain – namely an imbalance of a brain chemical called serotonin. However, our latest research review shows that the evidence does not support it. Although first proposed
How We Have Been Misled About Antidepressants
By JOANNA MONCRIEFF (UCL) Our umbrella review that revealed no links between serotonin and depression has caused shock waves among the general public, but has been dismissed as old news by psychiatric opinion leaders. This disjunction begs the questions of why the public has been fed this narrative for so long, and what antidepressants are actually doing if they